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WITH ESPECIAL REFERENCE TO ITS EFFECTS ON THE CAPILLARY FRAGILITY

IRVING S. WRIGHT, M.D.; ALFRED LILIENFELD, M.D.

Arch Intern Med. 1936;57(2):241-274.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The isolation of hexuronic acid from cabbages, orange juice and adrenal cortex by Szent-Györgyi¹ in 1928 opened a new field for investigation, which culminated in 1932 with its identification as crystalline vitamin C, now termed cevitamic acid.²

This substance is an odorless, white or yellowish-white crystalline powder, with a melting point of from 189 to 192 C. An outline of its properties follows:

Formula: The acid titration corresponds with the formula C₆H₈O₆.³

Solubility: It is freely soluble in water and also soluble in acetone, acetic ether and propyl alcohol, and insoluble in ethyl ether and purified petroleum benzine.⁴

Stability: It oxidizes on exposure to air and light. In an inert atmosphere it is quite stable to moderate heat, even in alkaline solution.⁵ It is decomposed when heated above 185 C.^3a

Reducing power: It has a high reducing power. This reducing power is the more remarkable since the . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Second Medical Division, Bellevue Hospital (Cornell University Medical College), Henry J. Spencer, M.D., director, and the Department of Medicine, New York Post-Graduate Medical School and Hospital (Columbia University), Herman O. Mosenthal, M.D., director.

Footnotes
This study was aided by a grant from the Josiah Macy Jr. Foundation Read before the Section of Medicine, New York Academy of Medicine, April 16, 1935.

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