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LIPID CONSTITUENTS OF THE NERVES CORRELATED WITH THE CLINICAL DATA

WILLIAM R. JORDAN, M.D.; L. O. RANDALL, B.S.

Arch Intern Med. 1936;57(2):414-421.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Contact with many persons with diabetes impresses one with the frequency of neuropathy in these patients. A study of this neuropathy from any approach is likely to be interesting and helpful in the present state of knowledge about it. The clinicians have noted evidence of degeneration, and the pathologists have partially confirmed their findings. We attempted to investigate this degeneration from the point of view of the fatty constituents of the nerves. The stains used by the pathologists indicated damage to the lipid sheath of the nerves but did not reveal the character of the change in detail.

In a previous paper¹ we reviewed the appropriate literature and gave a preliminary report of the results of the chemical analysis of twenty nerves of diabetic patients as compared with nerves from persons without diabetes. In the present paper are included analyses of thirty-two more nerves from diabetic patients and a . . . [Full Text PDF of this Article]

Author Affiliations
RICHMOND, VA.; ROCHESTER, N. Y.

From the Joslin Diabetic Clinic, Boston, and the Department of Biochemistry, University of Rochester, Rochester, N. Y.

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