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DISEASES OF METABOLISM AND NUTRITIONREVIEW OF CERTAIN RECENT CONTRIBUTIONS
RUSSELL M. WILDER, Ph.D., M.D.;
DWIGHT L. WILBUR, M.D.
Arch Intern Med. 1936;57(2):422-471.
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I. DISEASES OF METABOLISM BY DR. WILDER
DIABETES MELLITUS
In the past year has been added what promises to be another outstanding achievement in the treatment of diabetes. This is the preparation by Hagedorn,1 in Copenhagen, Denmark, of a compound of a protamine from salmon sperm and insulin. By virtue of a slow liberation of insulin a prolongation of the insulin effect is obtained, whereby wide fluctuations of values for blood sugar are avoided and the danger of reaction is lessened. The first printed announcement of the neo-insulin was made by Dr. Elliott P. Joslin2 in the new edition, the fifth, of "The Treatment of Diabetes Mellitus." The information came after the manuscript of the book was completed, and the announcement appears as an added paragraph at the end of chapter1.
The fifth edition of "The Treatment of Diabetes Mellitus" is itself a contribution of primary importance in
. . . [Full Text PDF of this Article]
Author Affiliations
ROCHESTER, MINN.
From the Division of Medicine, the Mayo Clinic.
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