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WITH SPECIAL REFERENCE TO THE ROLE OF THE ARSPHENAMINES

ROBERT V. SAGER, M.D.

Arch Intern Med. 1936;57(4):666-694.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

For at least four hundred years physicians have known of the occurrence of jaundice with syphilis (Paracelsus,¹ 1510). The introduction of arsphenamine seems to have increased the incidence and the complexity of this condition. Since in syphilis, as in any other disease, treatment is necessarily guided by the concepts of etiology, it is of paramount importance to determine the exact causes of the jaundice. To this end in the present study I proposed to investigate the factors concerned in the occurrence of jaundice with syphilis and to correlate them with recent acquisitions to the clinical, experimental and pathologic knowledge of disease of the liver.

In the discussion of this subject it is necessary at the outset to define certain terms and concepts that are employed. The term the arsphenamines is used to indicate the entire family of organic arsenical antisyphilitic preparations, all of which are associated with the condition . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Medical Service of Dr. B. S. Oppenheimer, The Mount Sinai Hospital.

Footnotes
This study was aided by a grant made to the Emanuel Libman Fellowship Fund in memory of Theresa Backer.

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