THERAPEUTIC EFFECT OF TOTAL ABLATION OF NORMAL THYROID ON CONGESTIVE FAILURE AND ANGINA PECTORISXVIII. THE CARDIAC OUTPUT FOLLOWING TOTAL THYROIDECTOMY IN PATIENTS WITH AND WITHOUT CONGESTIVE HEART FAILURE, WITH A COMPARISON OF RESULTS OBTAINED WITH THE ACETYLENE AND ETHYL IODIDE METHODS
MARK D. ALTSCHULE, M.D.;
MARIE C. VOLK, A.B.
Arch Intern Med. 1936;58(1):32-44.
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Studies of the cardiac output in spontaneous myxedema are few. Various observers1 have reported a decrease in the minute volume output of the heart in patients with hypothyroidism. The recently reported work of Blumgart and his associates2 in establishing the value of total ablation of the thyroid gland in the treatment of chronic intractable cardiac disease made it advisable to study the cardiac output and related aspects of the circulation in hypothyroidism induced by this operation. Data obtained by the acetylene method3 for seven patients with no evidence of congestive failure were reported in a previous publication.4 This communication presents preoperative and postoperative studies of the cardiac output by means of the ethyl iodide method5 in patients with and without congestive failure on whom total thyroidectomy was performed. Results obtained by this method and by the acetylene method in the same patients are compared.
MATERIAL
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Author Affiliations
BOSTON
From the Medical Service and Medical Research Laboratories of the Beth Israel Hospital and the Department of Medicine, Harvard University Medical School.
Footnotes
This investigation was aided by a grant from the William W. Wellington Memorial Research Fund of Harvard University.
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