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EXPERIMENTAL RENAL INSUFFICIENCY PRODUCED BY PARTIAL NEPHRECTOMYVII. THE RELATIONSHIP OF URINE UREA, BLOOD UREA AND UREA (ADDIS) RATIO IN RATS ON WHOLE DRIED MEAT DIETS
STEPHAN LUDEWIG, Ph.D.;
E. T. R. WILLIAMS, Ph.D.;
ALFRED CHANUTIN, Ph.D.
Arch Intern Med. 1936;58(1):89-94.
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The present study deals with the effect of feeding diets containing various concentrations of whole meat on the amount of urea in the urine and blood and the urea (Addis) ratio, urea excreted/blood urea in partially nephrectomized, unilaterally nephrectomized and intact rats.
The experimental procedure, the experimental diets and abbreviations were outlined in a previous paper.1 The data for all animals excreting less than 50 per cent of the urea solution administered were excluded. The previous data have been supplemented by values obtained at frequent intervals in individual animals.
RESULTS
The effect of various concentrations of whole dried meat on the amount of urea in the blood and urine and on the urea ratio, urea excreted per hour X 100, of partially nephrectomized and control aniurea in 100 cc. blood mals (unilaterally nephrectomized and intact) is shown in chart 1. Five phases of renal function are
. . . [Full Text PDF of this Article]
Author Affiliations
UNIVERSITY, VA.
From the Laboratory of Physiological Chemistry, the University of Virginia.
Footnotes
This investigation was made possible by a grant from the National Live Stock and Meat Board and by the Edward N. Gibbs Prize Fund of the New York Academy of Medicine.
The statistical analyses were performed by Dr. Williams, who is on the staff of the Leander McCormick Observatory.
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