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ETIOLOGIC SIGNIFICANCE OF STREPTOCOCCI IN EPIDEMIC ENCEPHALITISI. INCIDENCE OF STREPTOCOCCI IN CULTURES FROM PATIENTS WITH ENCEPHALITIS IN ST. LOUIS AND FROM NORMAL CONTROLS, AND CHARACTERISTICS OF THE VARIOUS STRAINS ISOLATED
KENNETH L. BURDON, Ph.D.;
ERIC W. THURSTON, M.D.;
PHILIP L. VARNEY, Ph.D.;
J. BRONFENBRENNER, Ph.D., D.P.H.
Arch Intern Med. 1936;58(2):285-308.
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The outbreak of acute epidemic encephalitis in St. Louis in the summer of 1933 offered an especially propitious opportunity to investigate the etiologic importance of streptococci in this disease as a parallel study to that being carried on with the filtrable virus by our associates. We were further stimulated to undertake this work by the presence in St. Louis of Dr. E. C. Rosenow, who was studying this same question and who was accumulating evidence similar to that advanced by him in the past indicating, in his opinion, the primary rôle of streptococci in the causation of the St. Louis form of the disease.
In view of the prominence of Rosenow's work in this field and in consideration of the fact that his results have been attained by following a special technic, our efforts were confined largely to a repetition of his studies, with as nearly as possible identical methods.
. . . [Full Text PDF of this Article]
Author Affiliations
ST. LOUIS
From the department of bacteriology and immunology, Washington University School of Medicine.
Footnotes
This investigation was undertaken as a part of the general study of the etiology of encephalitis conducted under the auspices of the Metropolitan Health Council of St. Louis during the epidemic of acute encephalitis in the summer of 1933. A summary appears in Public Health Bulletin 214 of the United States Public Health Service.
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