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NONBACTERIAL THROMBOTIC ENDOCARDITISCLASSIFICATION AND GENERAL DESCRIPTION
LOUIS GROSS, M.D.;
CHARLES K. FRIEDBERG, M.D.
Arch Intern Med. 1936;58(4):620-640.
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According to Libman,1 endocarditis may be classified as rheumatic, syphilitic, acute bacterial, subacute bacterial and indeterminate. The indeterminate group includes a number of heterogeneous types characterized by nonbacterial, verrucous endocardial deposits, which cannot clearly be placed under the preceding headings. Certain forms in this indeterminate group, occurring toward the end of chronic diseases like carcinoma, leukemia or nephritis, were called terminal endocarditis. These corresponded to the cachectic endocarditis mentioned by Harbitz.2 In 1923 Libman and Sacks3 further segregated from the instances of the indeterminate group four cases in which the clinical and pathologic features were sufficiently uniform to constitute a definite syndrome. Because of the peculiar appearance of the gross endocardial lesions in this group of cases, the condition was termed "atypical verrucous endocarditis." In 1932 one of us (L. G.)4 made a detailed study of the pathologic changes of the hearts of eleven patients with
. . . [Full Text PDF of this Article]
Author Affiliations
NEW YORK
From the Medical Services and the Laboratories of the Mount Sinai Hospital.
Footnotes
Aided by grants from the Lucius N. Littauer Fund and the Walter W. Naumburg Fund.
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