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REPORT OF SEVEN CASES WITH THREE DEATHS

WILLIAM GOLDRING, M.D.; IRVING GRAEF, M.D.

Arch Intern Med. 1936;58(5):825-845.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since recognition and classification of the blood groups have become general, serious posttransfusion reactions have been infrequent. However, the publication of Bordley's¹ report has focused attention on a striking syndrome following transfusion with incompatible blood. He reported three such reactions and, after extensive search of the literature, fourteen adequately described additional instances. Subsequently other observers have published their experiences with this reaction.² The clinical and pathologic similarities in all the cases reported are striking. There is sufficient evidence to indicate that the reaction is the result of hemolysis of the donor's incompatible red blood cells. A typical reaction is characterized by an immediate diminution in the output of urine (in instances of severe involvement, by complete suppression) and hemoglobinuria;³ within a few hours a moderate degree of icterus appears; the nonprotein nitrogen content of the blood rises gradually and within a few days reaches a high level, . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Medicine and the Department of Pathology, the New York University College of Medicine, and the Third (New York University) Medical Division and the Pathologic Laboratory, Bellevue Hospital.

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