This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

A. B. STOCKTON, M.D.

Arch Intern Med. 1936;58(5):891-900.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In previous papers I have discussed the concurrent changes in the output of urine and in the blood and urinary metabolites of animals and edematous patients treated with diuretic drugs.¹ The following drugs produced increases in the output of urine and in the chloride content of the blood and urine: sodium bismuth tartrate, theophylline, merbaphen and salyrgan. Bismuth caused the same effects in normal and chloride-saturated rabbits but much less pronounced changes in those deprived of chloride. In edematous patients the increase in the amount of urinary urea and of uric acid after the administration of bismuth paralleled the diuresis, and the concentration of these metabolites, the dilution of the urine. The hemoglobin, sugar, urea and uric acid contents of the blood showed no changes, or only negligible ones, after the administration of bismuth.

The effects on the chloride content during diuresis due to digitalis differed. This drug reduced . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO

From the Departments of Pharmacology and Medicine, Stanford University School of Medicine.

Footnotes
Supported in part by a grant from the Rockefeller Fluid Research Fund of the School of Medicine, Stanford University.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?