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R. H. FREYBERG, M.D.

Arch Intern Med. 1937;59(4):660-666.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In 1920 Newburgh and Squier¹ reported the occurrence of atherosclerosis in rabbits fed diets rich in animal protein. The diets used were of two kinds: one was a mixture of milk, scraped carrot and water to which casein was added; the other was a mixture of dried powdered beef and bread flour in the proportion 1:2. Although it appeared that the vascular lesions had been caused by the protein of the diets, such a conclusion was thought not to be warranted at that time because of the smallness of the group of experimental animals.

Later, investigation by Newburgh and Clarkson² showed conclusively that ingestion of muscle meat by rabbits results in extensive atherosclerosis of the aorta and other large arteries. Eight of eleven animals that were fed a diet containing 27 per cent protein derived chiefly from dried ground beef muscle for more than six months became atherosclerotic. . . . [Full Text PDF of this Article]

Author Affiliations
ANN ARBOR, MICH.

From the Department of Internal Medicine, the University of Michigan Medical School.

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