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FUNICULAR DEGENERATION OF THE SPINAL CORD WITHOUT PERNICIOUS ANEMIANEUROLOGIC ASPECTS OF SPRUE, NONTROPICAL SPRUE AND IDIOPATHIC STEATORRHEA
HENRY W. WOLTMAN, M.D.;
FRANK J. HECK, M.D.
Arch Intern Med. 1937;60(2):272-300.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Subacute combined degeneration of the spinal cord has come to involve a major problem that centers about the type of degeneration seen typically in pernicious anemia. More than sixty associated conditions or causes have been advanced for combined degeneration that often is said to be "just like that of pernicious anemia" (table 1). In some instances involvement of posterior and lateral columns, regardless of the absence of the usual status spongiosus or the presence of prominent fibrillar gliosis, fills the requirement of "like"; in others an occasional focus of perivascular demyelinization, regardless of its nature or topography, or degeneration of the posterior roots with secondary degeneration in the posterior column suffices; too much confidence may be placed in a typical or suggestive clinical picture of combined degeneration, or an unusual clinical picture may pass without comment. Criteria needed to rule out pernicious anemia or some kindred disturbance often are left
. . . [Full Text PDF of this Article]
Author Affiliations
ROCHESTER, MINN.
From the Department of Neurology and the Division of Medicine, the Mayo Clinic.
Footnotes
Read at the meeting of the Association of American Physicians, Atlantic City, N. J., May 6, 1936.
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