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STACY R. METTIER, M.D.; KATHERINE PURVIANCE, A.B.

Arch Intern Med. 1937;60(3):458-473.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

It is well known that leukemia may occur without leukocytosis. In such cases the clinical picture of weakness and pallor and the varying degrees of lymphadenopathy, splenomegaly and hepatomegaly, with the blood picture of anemia and thrombopenia and the presence of myeloblasts in the stained blood film, make the diagnosis possible. The anatomic findings in the cases hitherto reported¹ show a similarity to the anatomic picture in true leukemia. There is, however, relatively little to be found in the medical literature on the occurrence of leukemia without splenomegaly. In a recent review² on leukemia it was mentioned that there are instances in which no splenic enlargement is noted. Hirschfeld³ reported four cases of leukemia without splenomegaly, Ordway and Gorham⁴ reported one case and Kracke and Garver⁵ also described one case. Recently Parkes Weber⁶ reported a case of aleukemic myelosis without splenic enlargement in which the condition . . . [Full Text PDF of this Article]

Author Affiliations
Assistant Professor of Medicine; Research Assistant SAN FRANCISCO

From the Department of Medicine, the University of California Medical School.

Footnotes
Supported by a grant from the Christine Breon Fund for Medical Research.

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