This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

I. UTILIZATION OF INTRAVENOUSLY INJECTED SODIUM d-LACTATE BY NORMAL PERSONS

LOUIS J. SOFFER, M.D.; D. ALFRED DANTES, M.D.; ROBERT NEWBURGER, M.D.; HARRY SOBOTKA, Ph.D.

Arch Intern Med. 1937;60(5):876-881.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The object of these experiments was to study the utilization of sodium d-lactate by human beings both under normal conditions and in the presence of certain pathologic processes. D-lactic acid represents an intermediary stage in carbohydrate metabolism in the cycle involving striated muscle and liver. The confusion which has arisen concerning the conversion of lactic acid into glycogen is in part due to the failure to realize the difference in the nature of the utilization of the d and l forms. Thus, Meyerhof and Lohmann¹ pointed out that isolated hepatic tissue of the rat was able to synthesize carbohydrate from d-lactic acid but hardly from l-lactic acid. Cori and Cori² have pointed out that if 95 mg. per hundred grams of body weight of d-lactic acid per hour is injected into rats, there occurs no appreciable increase in the lactic acid content of either the blood or the urine, . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Medical Service of Dr. George Baehr and the Division of Laboratories, Mount Sinai Hospital.

Footnotes
Aided by a grant from Merck & Co., Inc.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?