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EDWARD J. VAN LIERE, M.D., Ph.D.; CLARK K. SLEETH, B.S.

Arch Intern Med. 1938;61(1):83-86.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

It has been suggested by various authors that digitalis causes an increase in gastric and intestinal motility. In the volume by Meyer and Gottlieb¹ entitled "Experimental Pharmacology," work (which was done in 1906) is reported on to the effect that digitalis glucosides influence gastric and intestinal peristalsis. Vail² by means of the roentgen ray observed that digitalis increased gastric motility. Cloetta³ stated that digitalis causes an increased gastric secretion. Since Hellebrandt⁴ has shown that gastric secretion and motility run parallel (at least during fasting), the observation of Cloetta is significant. A rather careful review of the literature, however, has failed to disclose any well controlled experiments which conclusively demonstrated that digitalis actually decreased the emptying time of the stomach. It was therefore thought worth while to investigate this problem. Material and data⁵ were at hand which facilitated the execution of this study.

METHODS

In seven . . . [Full Text PDF of this Article]

Author Affiliations
MORGANTOWN, W. VA.

From the Department of Physiology, the University of West Virginia.

Footnotes
This research was made possible through a grant from the Therapeutic Research Committee of the Council on Pharmacy and Chemistry of the American Medical Association.

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