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S. W. RANSON, Jr., M.D.

Arch Intern Med. 1938;61(2):285-296.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since vaccines of the typhoid group are administered intravenously in arthritis, iritis, thrombo-angiitis obliterans and other conditions and since there does not seem to have been any adequate study of the reaction caused by these vaccines, an inquiry into the more detailed nature of the normal response to the injection should serve a useful purpose. During a series of experiments designed to determine the effect of various hypothalamic lesions on the course of fever induced in cats by the intravenous injection of typhoid-paratyphoid vaccine, sixteen normal cats were studied.

Pinkston¹ recorded the inguinal temperature of twelve normal cats to which typhoid-paratyphoid vaccine had been administered intravenously. He made readings every 10 to 30 minutes "until the body temperature had started toward normal." Cannon and Pereira² described the temperature curves obtained for ten normal cats after intravenous or intramuscular injection of a suspension of dead typhoid bacilli. They did . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Institute of Neurology, Northwestern University Medical School, Chicago.

Footnotes
This study was aided by grants from the Rockefeller Foundation and the Committee on Scientific Research of the American Medical Association.

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