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A COMPARATIVE EVALUATION IN CLINICAL PRACTICE

MOSES PAULSON, M.D.; JUSTIN ANDREWS, Sc.D.

Arch Intern Med. 1938;61(4):562-578.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The first reference to the serologic diagnosis of amebiasis was made by Izar,¹ in 1914. He experimented with complement fixation, the technic on which the Wassermann reaction for the diagnosis of syphilis is based. While sporadic studies were subsequently made, it remained for Craig² (1927) to place this test on a relatively practical basis by improving the preparation of the antigen and standardizing the technic. Later attempts to improve the Craig test resulted in minor changes by Sherwood and Heathman³ (1932), Weiss and Arnold⁴ (1934) and Tsuchiya⁵ (1934). Each of these workers or pair of workers with a different modification of the test has corroborated, in the main, Craig's contention of the specificity of complement fixation in the diagnosis of amebiasis. Details of the history and development of this procedure have been treated adequately in Craig's⁶ excellent monograph entitled "Amebiasis and Amebic Dysentery" (1934).

Interest in amebiasis has greatly . . . [Full Text PDF of this Article]

Author Affiliations
BALTIMORE

From the Gastro-Intestinal Section of the Medical Clinic of the Johns Hopkins Hospital and Medical School and the Department of Protozoölogy, the Johns Hopkins School of Hygiene and Public Health.

Footnotes
Read at the annual meeting of the American Society of Tropical Medicine, Baltimore, Nov. 18, 1936.

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