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ENLARGEMENT OF THE LIVER IN DIABETIC CHILDRENII. EFFECT OF RAW PANCREAS, BETAINE HYDROCHLORIDE AND PROTAMINE INSULIN
PRISCILLA WHITE, M.D.;
ALEXANDER MARBLE, M.D.;
ISABEL K. BOGAN, M.D.;
RACHEL M. SMITH, A.B.
Arch Intern Med. 1938;62(5):751-764.
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In the preceding paper we1 discussed the general characteristics of hepatomegaly as seen in 60 diabetic children possessing this complication. The present report is concerned with the results of treatment with three agents; raw pancreas, betaine hydrochloride and protamine insulin.
METHODS
All the children were kept under close observation, and most of them spent one or more weeks in the hospital during the period of study. For the greater part of the time, however, the patients were at home, because of the expense and undesirability of prolonged hospitalization. One must accept the fact that the care taken by the patients and their families as regards diet and insulin probably varied somewhat from time to time, so that strictly comparable conditions throughout cannot be claimed. It is most likely that during the periods of special medication, as with betaine and with protamine insulin, more care was given also to other
. . . [Full Text PDF of this Article]
Author Affiliations
BOSTON
From the George F. Baker Clinic, Elliott P. Joslin, M.D., Medical Director, New England Deaconess Hospital.
Footnotes
This work was aided by a grant from the Chemical Foundation, Inc.
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