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REPORT OF A CASE WITH NECROPSY AND ANALYSIS OF THE LIVER

GERALD FLAUM, M.D.; GEORGE H. STUECK, Jr., M.D.

Arch Intern Med. 1939;63(3):433-444.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In his monograph on hemochromatosis (1935) Sheldon¹ accepted from the literature 311 cases of the disease. The incidence of hemochromatosis found at necropsy has been reported by Rowen and Mallory² as 0.05 per cent in a series of 6,500 autopsies. Blanton and Healy³ reported finding the condition at 0.08 per cent of 5,000 autopsies at Bellevue Hospital. The postmortem incidence reported from other sources ranged between 0.001 and 0.4 per cent. The diagnosis of the disease is made more often at autopsy than clinically, owing to the fact that pigmentation has been the factor which suggested the diagnosis. That cutaneous pigmentation is not an essential criterion for the diagnosis of hemochromatosis is well known. The four cardinal signs of the disease occur, according to Sheldon, in the following order: (1) enlargement of the liver (92 per cent), (2) pigmentation (84 per cent), (3) diabetes mellitus (78 per . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Medicine, New York University College of Medicine, and the Third (New York University) Medical Division, Bellevue Hospital.

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