This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

TREATMENT IN TWO CASES OF SEVERE DIABETES BY EQUALLY AND UNEQUALLY DIVIDED DIETS, WITH COMMENTS ON CRITERIA FOR TREATMENT

EDWARD TOLSTOI, M.D.; FREDERICK C. WEBER, Jr., M.D.

Arch Intern Med. 1939;64(1):91-104.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

During the past two years we have treated some of our diabetic patients, both in the outpatient department and in the hospital wards, with protamine zinc insulin. Like others,¹ we hoped that by virtue of its slow activity a single daily dose of this new preparation could be substituted for three or even four doses of regular insulin. However, when we put this thought into practice we experienced considerable difficulty in maintaining the urine free from sugar. We appreciated the facts that we employed the higher carbohydrate diet—200 to 250 Gm.—and that we had not worked out a technic for the use of protamine insulin. As a matter of fact, there is no definitely established technic for the administration of this preparation. All sorts of combinations² are recommended, with or without the addition of regular insulin—that is, two or more hypodermic injections daily. It was, and still is our . . . [Full Text PDF of this Article]

Author Affiliations
With the Technical Assistance of Vincent Toscani, B.S. NEW YORK

From the New York Hospital and the Department of Medicine, Cornell University Medical College, and the Russell Sage Institute of Pathology.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?