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  Vol. 64 No. 2, AUGUST 1939 TABLE OF CONTENTS
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POLYOSTOTIC FIBROUS DYSPLASIA

REPORT OF A CASE

THOMAS HORWITZ, M.D.; ABRAHAM CANTAROW, M.D.

Arch Intern Med. 1939;64(2):280-285.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The skeletal disease known as polyostotic fibrous dysplasia has been described in the literature under a variety of designations, including osteodystrophia fibrosa unilateralis, osteitis fibrosa localisata, osteodystrophia fibrosa cystica generalisata, fibrous osteodystrophy and osteitis fibrosa disseminata. Since the osseous changes, which in this condition are usually predominantly or exclusively unilateral, simulate roentgenographically those due to hyperparathyroidism (osteitis fibrosa cystica, Recklinghausen's disease of bone), it is essential to exclude the latter disease so that the patient may not be subjected to unnecessary exploration of the neck and thorax. The term "polyostotic fibrous dysplasia" was applied to this condition by Lichtenstein1 and Jaffe,2 each of whom described a rather characteristic histologic picture of the bone lesion. The present case is reported because it illustrates certain points of importance in differential diagnosis and because we feel that the possible presence of this disorder is frequently overlooked in cases in which the . . . [Full Text PDF of this Article]


Author Affiliations

PHILADELPHIA

From the Departments of Orthopedic Surgery and Medicine, Jefferson Medical College Hospital.



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