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By Charles Fisher, Ph.D.; W. R. Ingram, Ph.D., and S. W. Ranson, Ph.D., M.D. Price, $5. Pp. 212, with 71 illustrations. Ann Arbor, Mich.: Edwards Brothers, Inc., 1938.

Arch Intern Med. 1939;64(3):660.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

This monograph is concerned with the nervous and hormonal factors involved in the regulation of water balance and especially with the great increase in water exchange which characterizes the disease known as diabetes insipidus. The investigations were carried out in the Institute of Neurology of Northwestern University Medical School during the past six years. Although most of the facts presented have been published by the authors in various periodicals, it is highly pleasing to find them correlated and collected into one volume.

The principal method of study was the production of discrete lesions in various parts of the hypothalamus with the Horsley-Clarke stereotaxic instrument. Diabetes insipidus was produced in 85 cats and 2 monkeys. Among the final conclusions of the investigators are that the neural lobe of the hypophysis is an endocrine gland which plays an antidiuretic role in renal water balance and that diabetes insipidus is essentially a hypophysial . . . [Full Text PDF of this Article]

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