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CLINICAL IMPLICATIONS

CHARLES C. MACKLIN, M.D., Ph.D., F.R.S.C.

Arch Intern Med. 1939;64(5):913-926.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

EXPERIMENTAL INVESTIGATIONS

Pulmonic Interstitial Emphysema.

—That air, after it has broken from the pulmonic alveoli into the interstitial tissue of the lung, can travel along the sheaths of the pulmonary blood vessels, in artificial channels which it dissects for itself, to the root of the lung, and from there into the mediastinum, has been amply demonstrated in a series of experiments on cats and other animals.¹ The alveoli are made to leak by overinflating them, and so stretching and straining the walls. This is accomplished by passing a truncated catheter into a region of the lung (the lower lobe of the right lung is conveniently used) and blowing air into it, thus extending the alveolar walls and producing many small ruptures in their floors, which overlie the small branches of the pulmonary blood vessels. It is important to visualize clearly this locus of the leakage,² the area of . . . [Full Text PDF of this Article]

Author Affiliations
LONDON, ONTARIO, CANADA

From the Department of Histology and Embryology, the University of Western Ontario Medical School.

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