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REVIEW OF CERTAIN RECENT CONTRIBUTIONS

RUSSELL M. WILDER, M.D., Ph.D.; HARRY C. BROWNE, M.D.; HUGH R. BUTT, M.D.

Arch Intern Med. 1940;65(2):390-460.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

DIABETES MELLITUS

Genesis.

—(a) Pituitary Gland and Carbohydrate Metabolism: In last year's review¹ attention was directed to the significance of Young's production of permanent diabetes in dogs by repeated injections of crude extracts of anterior lobes of beef pituitaries for a long period. This work, together with the more significant literature that bears on the relation of the anterior lobe of the pituitary to carbohydrate metabolism, is reviewed by Young² in a readable paper which he gave before the section of physiology at the annual meeting (1939) of the British Medical Association. A tentative general conclusion from experiments of Long, Russell, Bennett³ and others assigns to the secretion of the anterior lobe of the pituitary a depressive action on the oxidation of carbohydrate in the muscles and promotion of glycogen storage. Since the storage of glycogen can be promoted also by crystalline adreno cortical substances,⁴ the suggestion is made that . . . [Full Text PDF of this Article]

Author Affiliations
Fellow in Medicine, the Mayo Foundation; ROCHESTER, MINN.; I. DISEASES OF METABOLISM By Dr. Wilder and Dr. Browne

From the Division of Medicine, the Mayo Clinic