This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

INTERMEDIARY FATAL FORM WITH ENLARGEMENT OF THE LIVER; A CLINICAL AND PATHOLOGIC STUDY

J. D. KIRSHBAUM, M.D.; H. POPPER, M.D.

Arch Intern Med. 1940;65(3):465-476.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Toxic hepatitis is known to both clinician and pathologist. Pathologists know the fatal form, acute yellow or red atrophy, characterized grossly by the small atrophic liver and microscopically by necrosis of the liver cells. Clinicians are more familiar with a nonfatal form of hepatitis, of which so-called catarrhal jaundice is typical. In cases of the latter condition the liver is usually enlarged, and since recovery is the usual outcome, knowledge of the pathologic changes is meager, except for a few histologic descriptions which are available from biopsies of the liver or from autopsy in cases of accidental death (Klemperer,¹ Schrumpf,² Popper,³ Eppinger and his associates⁴ and Aschoff⁵).

Eppinger⁶ was the first to state that catarrhal jaundice is the miniature form of acute yellow atrophy. The few histologic observations available confirm the statement, later supported by Gaskell,⁷ Boyd⁸ and others. Animal experiments with allylformiate intoxication by Popper⁹ have revealed the transition . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Department of Pathology of the Cook County Hospital and the Cook County Graduate School of Medicine.

Footnotes
Research Fellow in the Cook County Graduate School of Medicine.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?