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PALMER HOWARD FUTCHER, M.D.

Arch Intern Med. 1940;65(6):1192-1210.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

While it is generally accepted that acute infection caused by streptococci precedes acute glomerular nephritis in the majority of cases, the exact course of events linking the infection with the renal disturbance is far from clear. Nor is it known whether once the nephritis has manifested itself, chronic infection remains an important agent in prolonging the disease. Authorities differ in the relative emphasis they place on the role of infection in this respect. Among protagonists of the etiologic importance of foci of infection is Kollert,¹ who distinguished two types of infection. One is the "primary focus," a chronic, often long-standing obscure process, situated perhaps in a paranasal sinus, which renders the subject peculiarly reactive to the machinations of subsequent acute invasion by the same organism. In the latter, "precipitating infection," the second of the two types, Kollert saw a trigger mechanism which sets off the initial attack of nephritis, . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Medicine, Johns Hopkins University School of Medicine and Johns Hopkins Hospital, Baltimore.

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