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ROBERT E. KAUFMAN, M.D.

Arch Intern Med. 1940;66(5):1079-1086.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In the past few years there has been considerable interest in the relationship between carbohydrate metabolism and vitamin B₁. As Williams and Spies¹ pointed out in their recent monograph: "There is convincing evidence of frequent disturbances of glycogen storage and blood sugar in B₁ avitaminosis. Further indications of this are found in clinical experience. A hyperglycemia and glycosuria in depancreatized dogs which does not respond to insulin but is cured by thiamin plus riboflavin has been reported. The whole matter of vitamin B¹ deficiency in relation to sugar disturbances requires further study, as the evidence of some association of the two is strong but still obscure." Monauni² claimed that thiamine is a two-sided regulator of blood sugar, raising the level when it is subnormal and lowering it when it is elevated. Several authors³ have shown that thiamine lowers the level of blood sugar and improves the sugar tolerance curve. Unfortunately, . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Diabetes Clinic of the Medical Division of the Lenox Hill Hospital.

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