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AN ANALYSIS OF THE RECORDS OF 1,469 PATIENTS TREATED IN THE LOS ANGELES COUNTY HOSPITAL FROM 1934 TO 1938 INCLUSIVE III. TYPE-SPECIFIC ANTIPNEUMOCOCCUS SERUM THERAPY: QUANTITATIVE RELATIONS BETWEEN DOSAGE AND RESULTS

FREDERICK J. MOORE, B.A.; ROY E. THOMAS, M.D.; BURRELL O. RAULSTON, M.D; ANSON HOYT, M.D.; JOHN D. WALTERS, B.A.

Arch Intern Med. 1941;67(2):286-303.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Treatment of pneumococcic pneumonia with type-specific antipneumococcus serum has received wide attention.¹ "Adequate" treatment is said to hasten recovery and improve the outcome. Three major factors determine the "adequacy" of serum: the duration of the untreated disease, the total amount of serum given and the rapidity of its administration. It is reasonable that these factors are interdependent in such a way that the relations between them are quantitative and amenable to analysis.

MATERIALS AND METHODS²

In the preceding articles³ certain data have been presented concerning all (1,469) patients with typed pneumococcic pneumonia treated in the Los Angeles County Hospital during the five year period 1934 to 1938. Of these, 569 received specific serum therapy, but 56 cases were discarded because the records were inadequate. The remaining 513 are otherwise unselected.

All patients received commercial type-specific, horse or rabbit antipneumococcus serum intravenously, in various hospital services, at the order . . . [Full Text PDF of this Article]

Author Affiliations
LOS ANGELES

From the Department of Medicine, School of Medicine, University of Southern California and from the Los Angeles County Hospital.

Footnotes
This study was aided by the Pneumonia Fund of the School of Medicine, University of Southern California.