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By Jean Vague and Jean Dunau. Price, $1.40. Pp. 185. Paris: Masson et Cie, 1939.

Arch Intern Med. 1941;67(2):469-470.

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In this monograph the authors have undertaken, with a high degree of success, to survey and interpret the present status of knowledge with regard to the chemistry, physiology and pathology of creatine and creatinine. Although emphasis is placed on developments in the subject since the discovery of phosphocreatine, the historical background has not been neglected, and the book is actually a review of the entire field. Preliminary chapters deal with the chemistry, determination and distribution of these compounds. A section is devoted to the relation of creatine to phylogenetic and ontogenetic development. The problem of the precursors of creatine is discussed and left as an open and important question still to be answered. In the following chapters, by means of an exposition of experimental and clinical observations, such subjects are treated as the role of creatine in the body, especially as an essential element in metabolism in muscle, and also . . . [Full Text PDF of this Article]

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