This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

AN ESTIMATION OF THE DAILY REQUIREMENT OF ASCORBIC ACID

GRACE A. GOLDSMITH, M.D.; ADOLPH T. OGAARD, M.D.; DONALD F. GOWE, M.D.

Arch Intern Med. 1941;67(3):597-608.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The relationship of vitamin C to hypersensitiveness has been the subject of numerous investigations in experimental animals, with conflicting and inconclusive results. The few studies of ascorbic acid and human hypersensitivity have likewise yielded divergent findings. Walzer,¹ in a recent review, concluded that no definite role for vitamin C in the immunologic mechanism of hypersensitiveness had as yet been established.

Our interest in this subject was stimulated during a study of vitamin C nutrition in the clinic and hospital population when we noted that a number of patients with bronchial asthma showed a low level of ascorbic acid in the blood plasma. Several reports of the use of ascorbic acid in the treatment of bronchial asthma have appeared, but no studies have been made of the state of vitamin C nutrition prior to therapy. Hochwald² found that ascorbic acid administered regularly was valuable in preventing symptoms of bronchial . . . [Full Text PDF of this Article]

Author Affiliations
NEW ORLEANS

From the Department of Medicine, Tulane University of Louisiana School of Medicine, and the Charity Hospital of Louisiana.

Footnotes
Formerly of New Orleans; now at St. Luke's Hospital, Ponce, Puerto Rico.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?