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EFFICACY OF THE PROJECTED DOSE METHOD OF TREATING PNEUMONIA WITH HOMOLOGOUS REFINED AND UNCONCENTRATED RABBIT ANTIPNEUMOCOCCUS SERUM

ELMER H. LOUGHLIN, M.D.; SAMUEL H. SPITZ, M.D.; RICHARD H. BENNETT, M.D.

Arch Intern Med. 1941;68(1):121-133.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

During the past year pneumococcic pneumonia was treated almost exclusively with chemotherapeutic substances. Pneumonia during this period was relatively mild, and bacteremia was infrequent. A decreased mortality rate for pneumonia, which could not be attributed entirely to specific measures, was noted. We feel, therefore, that a study of the results obtained with a specific therapeutic agent during a previous period in which pneumonia was known to be more severe and in which there was a higher incidence of bacteremia should be presented at this time.

Rabbit antipneumococcus serum was first used by Horsfall, Goodner and MacLeod¹ in 1936. In 1937, these authors and an associate² described 22 cases in which this serum was used. In 1938, the first three authors reported the results obtained with homologous serum in 67 cases of types I, II, III, V, VI, VII, VIII, XIV and XVIII pneumococcus pneumonia in which the mortality . . . [Full Text PDF of this Article]

Author Affiliations
BROOKLYN

From the Department of Internal Medicine, Long Island College of Medicine.

Footnotes
The rabbit antipneumococcus serum used in the cases reported in this paper was supplied by the Lilly Research Laboratories.

This work was made possible by a fellowship grant from the Lilly Research Laboratories, Indianapolis, and by aid from the Dr. Frank E. West Fund, established by Miss Elizabeth Frothingham, and from the John C. Warren Memorial Fund, established by Dr. Luther F. Warren, in memory of his son.

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