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INFLUENCE OF ACACIA, INJECTED INTRAVENOUSLY, ON CONCENTRATION OF PROTEINS AND ON COLLOID OSMOTIC PRESSURE OF THE SERUM

ARNOLDUS GOUDSMIT, Jr., M.D.; MELVIN W. BINGER, M.D.; MARSCHELLE H. POWER, Ph.D.

Arch Intern Med. 1941;68(4):701-712.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The intravenous administration of solution of acacia to patients with a nephrotic type of edema is being employed by many physicians. Two of us (Goudsmit and Binger¹) recently reviewed the literature on such treatment and reported experiences with this therapeutic adjunct in 40 cases, in 36 of which the patients were effectively and rapidly relieved of their edema. No harmful effects were noticed.

It has been tacitly assumed by most investigators that the colloid osmotic pressure of the serum is increased after the introduction into the blood stream of quantities of acacia such as were employed with favorable results. Indeed, Kerkhof² reported 1 case in which there was extensive nephrotic edema and the serum exerted a colloid osmotic pressure of 8 mm. of mercury (109 mm. of water). Three hundred grams of acacia in 30 per cent solution was given in the course of three days. One hour . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA; ROCHESTER, MINN.

From the Division of Medicine of the Mayo Clinic (Dr. Binger) and the Division of Biochemistry of the Mayo Foundation (Dr. Power).

Footnotes
At the time this work was done Dr. Goudsmit was a Fellow in Medicine of the Mayo Foundation.

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