This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

REPORT OF THREE FATAL CASES OF TULAREMIA, WITH BRIEF NOTES ON TWO OTHERS

JOHN C. RANSMEIER, M.D.; ISABELLE G. SCHAUB, B.A.

Arch Intern Med. 1941;68(4):747-762.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE OCCURRENCE OF BACTEREMIA

The concept of invasion of the blood stream in tularemia is embodied in the name given to the disease by Francis,¹ who wrote: "The name tularemia is based upon the specific name Bacterium tularense, plus -aemia, from the Greek, and has reference to the presence of this bacterium in the blood." In early investigations direct proof of bacteremia was furnished by animal inoculation. Blood from a patient with "deer-fly fever" who ultimately recovered was injected into guinea pigs by Francis¹ (case 3) and was found to be infectious. Simpson² similarly recovered the organism in 1 nonfatal case (XI) and also in a rapidly fatal case in which the blood was taken on the day before death. Such observations have been amply confirmed by others who have demonstrated by guinea pig inoculation the presence of B. tularense in the blood in fatal cases, both . . . [Full Text PDF of this Article]

Author Affiliations
NASHVILLE, TENN.; BALTIMORE

From the Departments of Medicine, and Pathology and Bacteriology, the Johns Hopkins University School of Medicine.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?