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CAPSULAR POLYSACCHARIDE IN THE BLOOD OF PATIENTS WITH PNEUMOCOCCIC PNEUMONIADETECTION, INCIDENCE, PROGNOSTIC SIGNIFICANCE AND RELATION TO THERAPIES
SAMUEL CHARLES BUKANTZ, M.D.;
PAUL F. de GARA, M.D.;
JESSE G. M. BULLOWA, M.D.
Arch Intern Med. 1942;69(2):191-212.
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We recently reported on the systematic examination for circulating capsular polysaccharide in the blood of 26 patients treated for pneumococcic pneumonia.1 It is generally recognized that the presence of bacteremia increases the gravity of the prognosis of the disease. It appeared from our earlier observations that the occurrence of free polysaccharide, which is more rapidly detectable than bacteremia, makes the prognosis even graver.
In this paper are reported the cases of 109 additional patients with pneumonia due to Pneumococcus type I, II, III, IV, V, VII or VIII and are presented the data on 135 patients frequently studied for the presence of polysaccharide. The patients, who had ample clinical, and usually roentgenologic, evidence of lobar pneumonia, were studied in the pneumonia service of Harlem Hospital. Before treatment was instituted samples of sputum for typing and of blood for
MATERIALS AND METHODS
The patients, who had ample clinical, and usually
. . . [Full Text PDF of this Article]
Author Affiliations
Clinical Professor of Medicine, New York University College of Medicine, and Visiting Physician, Harlem Hospital NEW YORK
From the medical service, Harlem Hospital; the Department of Hospitals of New York City, and the Littauer Pneumonia Research Fund of New York University College of Medicine.
Footnotes
Littauer Fellow in Pneumonia Research.
Dazian Fellow.
This study received additional financial support from the Metropolitan Life Insurance Company and from Mr. Bernard M. Baruch, Mr. Barnard M. Baruch Jr., Miss Belle N. Baruch and Mrs. Robert H. Samstag.
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