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A CLINICAL AND EXPERIMENTAL STUDY

R. H. RIGDON, M.D.; E. S. CARDWELL, M.D.

Arch Intern Med. 1942;69(4):670-690.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Sucrose has been widely used for tissue dehydration in such conditions as cerebral edema associated with trauma,¹ chronic hypertension,² acute alcoholism,³ status asthmaticus,⁴ postoperative anemia,⁵ edema of nephrosis and nutritional edema.⁶

The quantity and the concentration of sucrose given to patients have varied widely. Dyar and Matthew⁷ gave 400 cc. of a 25 per cent solution intravenously. These investigators found no contraindication to the use of sucrose except perhaps the presence of markedly low renal function. Masserman⁸ has given intravenously as much as 500 cc. of a 50 per cent solution of sucrose. He expressed the opinion that "comparatively large amounts of sucrose in the circulation are not toxic and cause no serious disturbances in the chemistry or cytology of the blood." Keith and Power⁹ found "the total excretion of the various urinary constituents during a day in which sucrose is injected but slightly altered aside from . . . [Full Text PDF of this Article]

Author Affiliations
MEMPHIS, TENN.

From the Department of Pathology, University of Tennessee.

Footnotes
This study was aided by a grant from the University of Tennessee.

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