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REPORT OF A CASE

WILLIAM I. GLASS, M.D.; CLIFFORD L. SPINGARN, M.D.; HERBERT POLLACK, M.D.

Arch Intern Med. 1942;70(2):221-235.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

There is no definite dextrose-insulin ratio applicable to all persons with diabetes. The amount of insulin needed to control the defective carbohydrate metabolism of any one patient must be determined empirically and may vary from time to time. Although diabetic persons with large insulin requirements are encountered infrequently, a number of cases of such requirement have been reported since the introduction of the hormone in 1922. These cases may be divided into two groups. In one the large insulin requirement is associated with some recognizable complication, such as diabetic ketosis, an infection, an endocrine disorder, hepatic disease or some other intercurrent illness. In the second there is no definite cause to account for the large amount of insulin that must be administered. This group, though small, includes some of the most extreme examples of huge insulin need.¹ Clinical and postmortem studies in such cases have revealed little to explain . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Second Medical Service and the Diabetic Clinic, Mount Sinai Hospital.

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