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  Vol. 72 No. 4, OCTOBER 1943 TABLE OF CONTENTS
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IMMUNE SERUM THERAPY FOR OROYA FEVER

CALDERON HOWE, M.D.

Arch Intern Med. 1943;72(4):429-438.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

No specific treatment has as yet been developed for Oroya fever, the severe and often fatal anemic stage of Carrión's disease. There have been from time to time numerous attempts at immune therapy with serum or transfusions of whole blood from patients convalescing or recovered from various stages of Carrión's disease.1 There have undoubtedly been many more trials at therapy along these lines than have been published. The few reports available, however, are inconclusive and neither substantiate nor detract from the possibility that such forms of passive immunization may be beneficial in certain cases.

In the field of chemotherapy, arsenical preparations have been tried by certain investigators2; but the evidence for any consistent success in this direction has been entirely unconvincing.

The present communication deals with 3 cases of Oroya fever in which hyperimmune rabbit serum containing a high titer of agglutinins for Bartonella bacilliformis was given in . . . [Full Text PDF of this Article]


Author Affiliations

BOSTON

From the Department of Comparative Pathology and Tropical Medicine, Harvard Medical School, and the National Institute of Hygiene and Public Health, Lima, Peru.


Footnotes

This investigation was financed in part from the Repayments Fund of the Department of Comparative Pathology and Tropical Medicine, Harvard Medical School.



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