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TRANSFUSIONS OF BLOOD FORTIFIED BY ADMINISTRATION OF VITAMIN K TO DONORS

MAJOR ROY E. KINSEY

Arch Intern Med. 1944;73(2):131-137.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The study of vitamin K and its relation to coagulation of blood has been completed in many of its details, with most of the research following three lines of investigation.

The first is based on the work of Dam,¹ who observed that when chicks were placed on a diet low in fat, a hemorrhagic disease developed. He demonstrated that this was a specific avitaminosis and that the bleeding tendency was due to hypoprothrombinemia. It has been further shown that this deficiency can be cured by feeding extracts of alfalfa or putrefied fish meal.

The second is based on the well known fact that patients with obstructive jaundice and biliary fistula acquire hemorrhagic tendencies and that the likelihood of bleeding increases with the length of time and the completeness with which bile is excluded from the intestinal tract. Warner, Brinkhous and Smith² and Butt, Snell and Osterberg³ almost . . . [Full Text PDF of this Article]

Author Affiliations
MEDICAL CORPS, ARMY OF THE UNITED STATES

Footnotes
Prepared under the supervision of Colonel Charles B. Callard, Medical Corps, United States Army, from records of patients in the Station Hospital, Camp Blanding, Fla.

Lieutenant Colonel Duward O. Wright and Major Jere Annis, Station Hospital, Camp Blanding Fla., cooperated in this work and made many helpful suggestions.

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