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III. A STUDY OF THE SIMULTANEOUS INFECTION OF A LARGE NUMBER OF MEN BY A SINGLE TYPE

LOWELL A. RANTZ, M.D.

Arch Intern Med. 1944;73(3):238-240.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

It is well known that varying amounts of circulating antibacterial and antitoxic antibodies are present in the serums of many persons, that increases in these immune substances may be expected to occur following infections and that the magnitude of the immune response differs from individual to individual. Rarely, if ever, have actual measurements of these antibodies been made for large groups of human subjects simultaneously infected with a single strain of micro-organism.

An unusual opportunity to perform such studies became available recently when an outbreak of streptococcic pharyngitis occurred in an Army camp. Many of the clinical details of this epidemic have been described elsewhere,¹ but they may be summarized here. Within sixty hours more than 300 men were admitted to the hospital suffering from typical hemolytic streptococcus tonsillitis or pharyngitis of varying degrees of severity. Approximately 20 per cent of them had a rash and presented the clinical . . . [Full Text PDF of this Article]

Author Affiliations
With the Technical Assistance of Georgiana Dole San Francisco

From the Department of Medicine, Stanford University School of Medicine, Stanford University Hospitals.

Footnotes
These investigations were aided through the Commission on Hemolytic Streptococcal Infections, Board for the Investigation and Control of Influenza and Other Epidemic Diseases in the Army, Preventive Medicine Division, Office of the Surgeon General, United States Army.

The work described in this paper was done under contract recommended by the Committee on Medical Research between the Office of Scientific Research and Development and Stanford University.

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