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EXPERIMENTAL HYPOPROTEINEMIA AND EDEMASTUDIES OF INTESTINAL ABSORPTION AND INTESTINAL ROENTGENOLOGIC CHARACTERISTICS
ARGYL J. BEAMS, M.D.;
ALFRED H. FREE, Ph.D.;
JACK R. LEONARDS, Ph.D.
Arch Intern Med. 1944;73(5):397-402.
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Comprehensive investigations have been made of the relationship between various deficiency states and the gastrointestinal tract which have resulted in the implication of many deficiencies as causes of disturbed gastrointestinal function. Anorexia, vomiting, diarrhea and other gastrointestinal dysfunctions have been noted in deficiency states,1 and experimental studies have shown that there are changes in the motility of the stomach and intestine.2 The influence of protein deficiency on the gastrointestinal tract has specifically been studied. Barden, Ravdin and Frazier3 and also Mecray, Barden and Ravdin4 have shown that the emptying time of the stomach of man and of the dog is noticeably prolonged in the presence of a definite hypoproteinemia, the gastric emptying time varying inversely with the level of plasma proteins. These investigators have also stated the belief that hypoproteinemia may produce so striking an effect on the gastrointestinal tract that severe mechanical defects may
. . . [Full Text PDF of this Article]
Author Affiliations
CLEVELAND
From the Departments of Medicine and Biochemistry, School of Medicine, Western Reserve University, and the University Hospitals.
Footnotes
This investigation was in part supported by a grant from the Williams-Waterman Fund of the Research Corporation.
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