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REPORT OF A CASE, WITH REPEATED ISOLATION OF THE ORGANISM FROM THE BLOOD

WILLIAM M. HITZIG, M.D.; ADA LIEBESMAN, B.A.

Arch Intern Med. 1944;73(5):415-424.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Clinical syndromes following rat bite have been ascribed to two micro-organisms, Streptobacillus moniliformis (Streptothrix, as originally described by Schottmüller) and Spirillum minus. The latter organism is of special interest in connection with the case about to be reported.

The present concept that rat bite fever is due to infection with a spirillum dates back to 1916, when Futaki, Takaki, Taniguchi and Osumi¹ described an unnamed spirochetal microorganism as "the cause of rat-bite fever." One year later Futaki and his associates² termed this organism Spirochaeta morsus muris. On the basis of morphologic characteristics, especially the rigid body and the terminal flagellums, Robertson³ preferred to classify the causal agent of rat bite fever (sodoku) as a spirillum. In view of the resemblance of the terminal flagellums to the minus sign, he proposed to adopt the name Spirillum minus, originally given by Carter,⁴ for an organism isolated from a . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Laboratories and the Second Medical Service of Dr. Eli Moschcowitz, the Mount Sinai Hospital.

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