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OBSERVATIONS ON ITS ADMINISTRATION TO HUMAN BEINGS

SAMUEL D. JACOBSON, M.D.; CHARLEY J. SMYTH, M.D.

Arch Intern Med. 1944;74(4):254-257.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The intravenous administration of a solution of gelatin as a blood substitute for the treatment of clinical shock was first reported by Hogan¹ in 1915. However, this demonstration of the possible efficacy of gelatin solution was forgotten until the present need for an adequate substitute for plasma, brought on by the present war, stimulated renewed interest in the possibilities of this substance.² As a result of the recent increased interest gelatin is being studied more intensively. One of the important methods for evaluating any plasma substitute is to study its ability to relieve experimental shock in animals. However, the interpretations of data obtained from such experiments on animals are often complicated by many factors arising from the methods of producing experimental shock, and therefore conclusions from such experiments are not always applicable to the treatment of shock in human beings. This point has recently been stressed by Blalock. . . . [Full Text PDF of this Article]

Author Affiliations
ELOISE, MICH.

From the Department of Medicine of Wayne University, College of Medicine, Detroit, and the Eloise Hospital.

Footnotes
This study was aided by a grant from the Upjohn Company, Kalamazoo, Mich.

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