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  Vol. 75 No. 5, MAY 1945 TABLE OF CONTENTS
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EFFECTS OF SOME LIVER EXTRACTS ON CARBOHYDRATE METABOLISM

CAPTAIN JOSEPH E. SOKAL

Arch Intern Med. 1945;75(5):327-340.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

INTRODUCTION AND REVIEW OF THE LITERATURE

The announcement by Minot and Murphy of the successful therapy of pernicious anemia by a liver diet served as a strong stimulus to the preparation and study of liver extracts. Although the primary interest of investigators has been in the effect of various liver extracts on the hemopoietic system and most of the studies have been confined to patients with pernicious anemia, there has been some consideration of the action of such extracts on other organ systems. With the introduction of injectable extracts in particular, animal experiments have been performed and various side actions of liver preparations have been studied.

In the course of such studies of the systemic effects of orally and parenterally administered liver extracts, especially the latter, various observers have noted more or less striking effects on the carbohydrate equilibrium of the body. As might be expected with different men using . . . [Full Text PDF of this Article]


Author Affiliations

MEDICAL CORPS, ARMY OF THE UNITED STATES

From the Department of Physiological Chemistry, Yale University Medical School.


Footnotes

Dr. C. N. H. Long and Miss Edith Fry gave advice and criticism during the studies reported and made laboratory facilities available.



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