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COLD HEMAGGLUTINATION IN PRIMARY ATYPICAL PNEUMONIA AND OTHER COMMON INFECTIONS
LIEUTENANT CLIFFORD L. SPINGARN, (MC), U.S.N.R.;
LIEUTENANT JOHN PAUL JONES, (MC), U.S.N.R.
Arch Intern Med. 1945;76(2):75-87.
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Recent reports indicate that large amounts of a cold hemagglutinin appear frequently in the blood of patients with primary atypical pneumonia.1 Apparently, this is not true of patients with other common infections of the respiratory tract, such as pneumococcic pneumonia, the common cold, influenza and pulmonary tuberculosis.2 In view of the simplicity of the titration of cold agglutinin in the serum, this procedure promises to be of value as a practical aid in the differentiation of primary atypical pneumonia from the other common types of pneumonia. This differentiation is often difficult, since no clinical or laboratory finding is characteristic of the former syndrome.3
During the winter and spring of 1943-1944, we studied the phemonemon of cold hemagglutination in 115 patients with pneumonia, in 257 patients with other infections and in 100 normal hospital personnel. This was done to evaluate further the specificity and significance of high titers
. . . [Full Text PDF of this Article]
Author Affiliations
From the Department of Epidemiology, The United States Naval Hospital, Treasure Island, San Francisco, Calif.
Footnotes
This article has been released for publication by the Division of Publications of the Bureau of Medicine and Surgery of the United States Navy. The opinions and views set forth in this article are those of the writers and are not to be construed as reflecting the policies of the Navy Department.
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