 |
|
ETIOLOGY AND PATHOGENESIS OF RHEUMATIC FEVER
LOWELL A. RANTZ, M.D.;
PAUL J. BOISVERT, M.D.;
WESLEY W. SPINK, M.D.
Arch Intern Med. 1945;76(3):131-138.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
|
|
|
Rheumatic fever is the cause of much disability and of many deaths resulting from the acute process and from the chronic heart disease which so frequently follows. The investigation of preventive and therapeutic measures for the control of this serious disease has been greatly hampered by the failure of many studies to establish satisfactorily its etiology and pathogenesis.
During the past twenty years it has become increasingly apparent that infection by hemolytic streptococci is in some way related to the development of the rheumatic state. The evidence on which this fact has been based has been of an indirect nature and may be summarized as follows: 1. Rheumatic fever has been observed to follow known hemolytic streptococcus infections, particularly of the respiratory tract. In these circumstances it has been noted that the initial acute illness is usually followed by a latent or quiescent period, which terminates in the more or
. . . [Full Text PDF of this Article]
Author Affiliations
SAN FRANCISCO NEW HAVEN, CONN. MINNEAPOLIS
Footnotes
Colonel T. E. Harwood Jr., Major James Blanton and Captain Howard Coggeshall cooperated and assisted in this work.
The laboratories of the Department of Medicine, Stanford University School of Medicine, were made available to the Commission on Hemolytic Streptococcal Infections for certain studies.
This investigation was carried out during a field study by the Commission on Hemolytic Streptococcal Infections, Board for the Investigation and Control of Influenza and Other Epidemic Diseases in the Army, Preventive Medicine Service, Office of the Surgeon General, United States Army.
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
|
