This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (101)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Sixty Cases Studied at Necropsy

DAVID M. SPAIN, M.D.; BERNARD J. HANDLER, M.D.

Arch Intern Med. 1946;77(1):37-65.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

COR PULMONALE is usually classified into the acute, subacute and chronic types. Acute cor pulmonale is generally caused by massive pulmonary emboli. If over 60 per cent of the vascular bed is occluded in this form, death will result almost immediately. The subacute form, the least frequent of the three, has been accurately described by Greenspan.¹ Secondary endolymphatic carcinomatosis of the lungs is the commonest cause of subacute cor pulmonale. In this condition the metastatic carcinoma diffusely infiltrates the perivascular lymphatics and then secondarily involves the pulmonary arterioles. This involvement interferes with the flow of blood through the pulmonary circuit and results in an increased burden on the right ventricle with eventual failure. The primary site for this type of secondary carcinomatous involvement of the lung is most often in the stomach, but in our experience carcinoma arising in the prostate, liver, kidney, breast or bronchus has also given . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Laboratory of Pathology, Bellevue Hospital; Department of Pathology, New York University College of Medicine, and First Medical Division (Columbia University), Bellevue Hospital.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?