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A Review of the Recent Literature

FRANK H. BETHELL, M.D.; CYRUS C. STURGIS, M.D.; R. WAYNE RUNDLES, Ph.D., M.D.; MURIEL C. MEYERS, M.D.

Arch Intern Med. 1946;77(2):196-234.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

BONE MARROW

Osgood and Seaman³⁷⁷ state after a review of the literature that wide discrepancies in the published values for normal marrow cells obtained by sternal puncture are due to uncritical acceptance of subjects as normal, differences in the quantity of material aspirated with a consequent variable degree of dilution of marrow with blood and lack of uniform criteria for identification of cells and terminology. They conclude that normal standards for aspirated marrow must await further studies. The authors advocate withdrawal of at least 1 cc. of material, since the cellular composition is not greatly affected by variations in volume in excess of 1 cc. The aspirated material should then be placed in a tube containing 2 mg. of potassium oxalate and thoroughly shaken. A count is made of nucleated cells, and films are prepared and stained with Wright's stain. Differential counts, which often are . . . [Full Text PDF of this Article]

Author Affiliations
ANN ARBOR, MICH.

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