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An Evaluation in Tonsillitis, Nasopharyngitis and Scarlet Fever

WESLEY W. SPINK, M.D.; LOWELL A. RANTZ, M.D.; PAUL J. BOISVERT, M.D.; CAPTAIN HOWARD COGGESHALL

Arch Intern Med. 1946;77(3):260-294.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ACUTE infections of the upper respiratory tract due to hemolytic streptococci, while constituting an important health problem in a civilian population, become accentuated during the time of war. This applies particularly to groups of military personnel during the early training period. Several reports have recorded attempts to control hemolytic streptococcus infections in military personnel, and the efforts have not been without some success.¹ The use of the sulfonamide compounds in the treatment of streptococcic infections of the upper respiratory tract has resulted in conflicting reports concerning the effectiveness of these drugs.² Until the present investigation was initiated and completed, no well controlled studies of penicillin in the therapy of infections of the upper respiratory tract, including scarlet fever, had appeared. Plummer and colleagues³ have recorded the results of penicillin therapy in 28 cases of acute pharyngitis-tonsillitis due to group A hemolytic streptococci. No Patients with scarlet fever were treated. There . . . [Full Text PDF of this Article]

Author Affiliations
MINNEAPOLIS; SAN FRANCISCO; NEW HAVEN, CONN.; MEDICAL CORPS, ARMY OF THE UNITED STATES

Footnotes
This investigation was carried out during a field study by the Commission on Hemolytic Streptococcal Infections, Board for the Investigation of Epidemic Diseases, United States Army.

The penicillin was provided by the Office of Scientific Research and Development from supplies assigned by the Committee on Medical Research for investigations recommended by the Committee on Chemotherapeutic and Other Agents of the National Research Council.

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