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SHOLOM O. WAIFE, M.D.; PEYTON T. PRATT, M.D.

Arch Intern Med. 1946;78(1):42-48.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SINCE the introduction of organic mercurial diuretics about twenty-five years ago¹ innumerable injections of such compounds as merbaphen (U. S. P. XI), mersalyl and mercurophylline have been given. Although toxic reactions have been reported they are amazingly few compared to the huge quantities administered. DeGraff and Nadler² summarized the literature on toxic manifestations of mercurial diuretics. They reported 26 deaths in sixteen years. No deaths have been reported from administration of the diuretics intramuscularly. Toxic reactions reported fall into three groups. Some reactions were due to the profuse diuresis.³ Other reactions or death followed suddenly after one or two doses of mercurial diuretics.⁴ These were probably the anaphylactoid reaction which might be due to any foreign agent. In some cases, mersalyl apparently caused tubular damage to the kidney.⁵

This case is being reported because, as far as can be determined, it is the first in . . . [Full Text PDF of this Article]

Author Affiliations
BALTIMORE; BROOKLYN

From the Departments of Medicine and Pathology of Long Island College of Medicine, Brooklyn, N. Y.

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