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II. Effectiveness of Intensive Salicylate Therapy in Cases of Acute Infection

COMMANDER R. C. MANCHESTER, MC

Arch Intern Med. 1946;78(2):170-180.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ACUTE rheumatic fever in young adults either in naval service¹ or in civilian life² begins primarily as an acute infection exhibiting acute polyarticular arthritis as the major manifestation. The disabling character of the acute polyarticular manifestations results in early medical care in most instances, before irreparable visceral damage necessarily occurs or the chronicity of infection becomes fixed. Therefore, a therapeutic regimen which succeeds in modifying the natural course of the disease offers the opportunity of preventing these unfortunate sequelae. This paper deals with the effectiveness of intensive salicylate therapy by the Coburn technic³ in accomplishing these objectives.

The essential problems in the treatment of acute rheumatic fever are: the alleviation of acute articular, visceral and toxic manifestations; the prevention, or lessening of the degree, of permanent cardiac damage; the shortening of the over-all period of active infection and the prevention of relapses and residual chronic infection.

While . . . [Full Text PDF of this Article]

Author Affiliations
U.S.N.R.

Footnotes
This article has been released for publication by the Division of Publications of the Bureau of Medicine and Surgery of the United States Navy. The opinions and views set forth in this article are those of the writer and are not to be construed as reflecting the policies of the Navy Department.

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